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Sebia is one of the HbA1c testing major actor as a global diagnostic company. Capillary electrophoresis is the next generation separation method that provides clear-cut and precise separation of the HbA1c fraction with no altered results in the presence of the most frequent interferences (labile A1c, carbamylated Hb, HbF, heterozygous S, C, D and E). The high resolution power of the method allows the incidental detection of homozygous hemoglobin variants (sicke cell disease,…) preventing HbA1c.